By Hanno Millesi, Robert Schmidhammer
Around the globe learn is happening to enhance the end result of the therapy of peripheral nerve lesions. but, there exist many questions, equivalent to: Is the autologeous nerve grafting nonetheless the golden ordinary in bridging defects? Have replacement concepts to beat defects reached a degree to interchange autografting? What might be anticipated from finish to facet coaptation? The contributions during this booklet provide solutions to all of those questions.
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Extra resources for How to Improve the Results of Peripheral Nerve Surgery (Acta Neurochirurgica Supplementum 100)
2a–c). Conclusions The C7-transfer proved to be a save transfer if at the time of operation no fascicles innervating wrist and ﬁnger extension are taken. Provided there is adequate biceps muscle organ function, active elbow ﬂexion can be reconstructed in most of the patients. However, for median nerve reinnervation motor results are moderate up to now. Acta Neurochir Suppl (2007) 100: 37–38 # Springer-Verlag 2007 Printed in Austria Bridging defects: autologous nerve grafts H. Millesi1;2 1 2 Millesi Center for the Surgery of Brachial Plexus and Peripheral Nerve Lesions, Vienna Private Clinic, Vienna, Austria Austrian Cluster for Tissue Regeneration, Ludwig Boltzmann Institute for Traumatology, Vienna, Austria Summary Autologous nerve grafting has been performed since 1876 without success.
Under halothane anaesthesia adult rats underwent unilateral sciatic nerve division, and proximal and distal nerve stumps were ligated and secured into silicone caps to prevent spontaneous regeneration. Treatment with N-acetylcysteine at doses of 300, 150, 10 and 1 mg=kg (n ¼ 5=group) commenced immediately postoperatively and was administered as a daily 1 ml intraperitoneal injection. 9% NaCl). The weight of the animals was assessed every three days and the dose adjusted accordingly. Two weeks following axotomy the L4 and L5 dorsal root ganglia were harvested bilaterally and ﬁxed in 4% paraformaldehyde.
Provided adequate biceps muscle organ function, active elbow ﬂexion can be reconstructed in most of the patients. However, for median nerve reinnervation motor results are moderate up to now. be Keywords: C7 Transfer; neurotization; donor nerve; brachial plexus lesion. Introduction Within the last decade contralateral C7-transfer has become a new source of axon donor in complete brachial plexus lesions. Patients and methods Ten adult patients with a complete posttraumatic brachial plexus lesion and a follow-up of more than 5 years are analyzed.