DNA Synthesis: Present and Future by R. H. Pritchard (auth.), Ian Molineux, Masamichi Kohiyama

By R. H. Pritchard (auth.), Ian Molineux, Masamichi Kohiyama (eds.)

This ebook represents the court cases of the NATO complicated learn Institute held in Santa Flavia, Sicily from the 20 - twenty ninth June, 1977. as well as the assessment talks given through the academics on the Institute it proved possible for different issues to be wonderfully reviewed. This has ended in a wider topic insurance than might another way were attainable. The dialogue classes which those evaluation talks have been tremendous worthwhile and just about all the individuals performed an lively function. basically the entire verbal contributions awarded at this ASI have been therefore positioned into written layout, that's why those complaints are so vast. ~hey do, notwithstanding, supply an up to date precis of DNA synthesis in a wide selection of topics with some of the last difficulties essentially expressed. The modifying of those contributions has been primarily constrained to changes common and presentation. we've taken a few liberties within the re-organization of the papers into comparable sections. We convey our due to those that helped manage the ASI and to the consultation conveners who tried to restrict and include those that turned too verbose. we're indebted to NATO, clinical Affairs department for the monetary help that made this ASI attainable. eventually, we show our gratitude to overlook Brenda Marriott. She typed all 75 papers during this publication, which was once initially envisioned to be lower than part its current size and which simply grew and grew. She merits our unique thanks.

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Trautner Ihnestrasse 63/73 1000 Berlin 33, W. Germany INTRODUCTION The initiation of chromosomal replication is the initial event in the bacterial cell cycle and all subseq"ent steps occur at a specific time after initiation. Thus the frequency of initiation determines the overall rate of DNA synthesis per cell, the amount of DNA per cell, and the rate of cell division (1). As one would expect from such an important cellular event, the steps involved in initiation have proven to be extremely complicated.

CABELLO, F. N. (1974) Proc. Nat. Acad. Sci. /1,4556 Stadler Symp. 44,45 Nature, 204, 7,71 Proc. Nat. Acad. J. Bacteriol. 117,488 51,262 39 REPLICATION ORIGIN OF B. D. and LEDERBERG, J. (1975) PLOC. Nat. Acad. Sci. 72,2207 (11) WINSTON, S. and MATSUSHITA, T. (1975) J. Bacteriol. (12) HARFORD, N. (1975) J. Bacteriol. (13) HARA, H. and YOSHIKAWA, H. (1973) 123,921 121,835 Nature New B~ol. (14) O'SULLIVAN, A. and SUEOKA, N. (1967) J. Mol. BioI. COLI. John E. Womack * and Walter Messer Max-Planck-Institut fUr molekulare Genetik Abt.

And Yura, T. 6. , Hashimoto, S. and Komano, T. 119: 811 7. L. B. 8. W. W. 9. lesser, W. (1972) 10. G. (1972) J. Mol. Biol. 11. E. and Zahn, G. (1975) In: DNA Synthesis and Its Regulation. (eds. M. Goulian and P. A. Benjamin, Inc. p602 12. E. and Messer, W. (1975) In: DNA Synthesis and Its Regulation (eds. M. Goulian and P. A. Benjamin, Inc. p618 13. H. L. 14. T. W. 129:1466 15. , 186:987 16. Wickner, S. and Hurwitz, J. 72 :921 17. , Fujiyama, A. and Kohara, A. (1975) In: DNA Synthesis and Its Regulation (eds.

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